Athlete's Heart Blog

Dr Larry Creswell

Dr. Larry Creswell on athletes and heart health.
About Larry / Contact

Writing on…

You are here: Home / Archives for athlete

More on Long-term Cardiac Risks of Endurance Sport

By 2 Comments

Last week I got an inquiry from Casey R. Ruff at the Simon Fraser University in Burnaby, British Columbia, Canada in response to my blog post, “Don’t Stop Running Yet!” from earlier this month.

Ruff wanted to share his report from earlier this year, entitled “Consequnces of decades of intense endurance training:  Is there a cardiovascular overtraining phenomenon?”  This is an excellent review of the data on this topic.  If you’re scientifically-minded, I would encourage you to give it a read.  If you’re interested in pursuing further reading, the reference list is extensive and useful.

The report makes the case for the hypothesis that intense endurance training over many years may produce unwanted heart disease.  The situation is summed up well in this figure which suggests a sweet spot, or “healthy zone,” for training volume.  Less or more exercise leads to greater heart disease risk over the long term.

I’ve noted before that many biological systems are known to have a “sweet spot” phenomenon.  This may be no different.

For the sake of balance, I shared some of my questions with Ruff:

1.  Is there any evidence for increased mortality rate or shorter life-expectancy because of participation in some sort of endurance sport?

2.  What explanation would you provide for the observation that most incidents of sports-related sudden cardiac death (SCD) occur in NON-veteran athletes?  And with autopsies that often show relatively unremarkable cardiac findings?

3.  Do you believe that veteran endurance athletes are at increased risk of SCD compared to non-veteran athletes?  And what is the magnitude of that risk?

4.  What are the consequences to the athlete who develops atrial arrhythmias?  How bad is that problem?

Ruff and his colleagues correctly suggest that further investigation with longitudinal studies are sorely needed.  I’m hopeful that with increased participation in endurance sports and increasing public dialog about this issue that these studies will be undertaken.

My Related Posts and Articles:

1.  Don’t Stop Running Yet!

2.  Short-term and Long-term Injury to the Heart with Exercise

3.  Ironman and Heart Health:  My Take on Things

Five Questions for Your Doctor

By 1 Comment

At my column this month at Endurance Corner I write about 5 questions athletes ought to be asking the doctor at their next visit.

I’ve written three other articles that address the value of a periodic check-up, how to find a good doctor, and how to deal with the cost of preventive care:

Spring Check-Up

How to Find a Doctor (For Athletes)

Six Tips for Athletes to Reduce the Cost of Preventive Care

Triathlon-Related Deaths: The Facts and What You Should Know

By Leave a Comment

In my column this month at Endurance Corner, I talk about my involvement with USA Triathlon’s Medical Review Panel.  I summarize some of the important facts about triathlon-related fatalities and offer some thoughts about how we might work together in the triathlon community to improve race safety.  It will require effort on the part of everybody involved–athletes, event organizers, and USA Triathlon and other governing bodies.

Heart Medications, WADA, and the Athlete

By 1 Comment

 

I occasionally get questions about athletes’ medications and the issue of doping, usually from amateur athletes who are simply concerned about breaking the rules of their sport.  I’m certainly not an expert at all of the aspects of doping rules, detection and enforcement efforts, and participation of various events/sports in organized anti-doping efforts, but it’s worth discussing some important points that will be generally applicable.

Many competitive sports will be involved with the efforts of the World Anti-Doping Agency (WADA).  So-called signatories to the WADA Anti-Doping Code agree to a set of policies, rules, and regulations that govern the conduct of their particular sports.  Current signatories include all organizations related to the broad Olympic Movement (eg, USA Triathlon, USA Swimming, USA Track & Field); many national sport organizations (eg, U.S. Anti-Doping Agency [USADA]); and various miscellaneous sports organizations (eg, World Karate Organization, World Triathlon Corporation [WTC]).  If you participate in activities of these organizations, the rules of the WADA Code apply to you and you should be familiar with these rules.

WADA periodically publishes a Prohibited List that outlines prohibited substances and methods.  The most recent List was published in August, 2011 and went into effect on January 1, 2012.  There are separate requirements for in- and out-of-competition settings and there are special rules that apply to certain sports.

With heart disease being so common in the American adult population, especially if we include hypertension, it’s worth drawing attention to several items on the Prohibited List:

1.  Non-approved substances.  Pharmacologic substances that are investigational (ie, not yet approved by a national regulatory agency) are prohibited at all times.

2.  Peptide Hormones, Growth Factors, & Related Substances are prohibited at all times.  Examples include erythropoeitin (EPO) and insulins.

3.  Beta-2 Agonists are used to treat asthma and other pulmonary diseases.  These medications are prohibited at all times EXCEPT for salbutamol (eg, Albuterol) or formoterol (eg, Symbicort) used at dosages in accordance with the manufacturer’s recommendations.  Athletes who use salbutamol or formoterol are subject to urine testing where levels of >1000 ng/mL or >30 ng/mL, respectively, indicate usage in excess of the manufacturer’s recommendations.

4.  Diuretics, in virtually every form, are prohibited at all times.  These medications (eg, hydrochlorothiazide [HCTZ], spironolactone, metolazone, acetazolamide) are common and are used alone or in combination with other agents to treat patients with high blood pressure and also in patients with heart failure.  They are on the Prohibited List because they can mask the detection of other agents on the List.

5.  Stimulants, in all forms, are prohibited during competition EXCEPT for a small group of stimulants included in the 2012 Monitoring Program:  caffeine, nicotine, phenylephrine, phenylpropanolamine, pipradol, and synephrine.

6.  Narcotics are prohibited during competition.

7.  Cannabinoids (ie, marijuana) are prohibited during competition.

8.  Alcohol is prohibited during competition for the following sports:  aeronautic, archery, automobile, karate, motorcycling, powerboating.

9.  Beta-Blockers (eg, atenolol, carvedilol, metoprolol) are prohibited during competition for the following sports:  aeronautic, archery (also, out-of-competition), automobile, billiards, boules, bridge, darts, golf, ninepin and tenpin bowling, powerboating, shooting (also, out-of-competition), and skiing/snowboarding.

I suspect that there are many amateur athletes participating in a sport governed by the WADA Code who are using one or more of these substances.  Armed with some knowledge about the rules, one logical approach might be to have a discussion with your doctor about alternative(s) to the prohibited medications.  Sometimes there might be a viable alternative.  Other times, a particular agent may well be the most appropriate choice of medication for a given athlete with a specific medical problem.  In that case, there is an oppotunity to obtain a Therapeutic Use Exemption (TUE)–permission to use a prohibited substance because of its medical necessity.  Information about the TUE application process is available through WADA.  Athletes will file applications with either their sport’s international federation or their country’s anti-doping agency.